Trophies - Successfully complete one of the following tasks to get a trophy:

Treasure! (Bronze): Unlock first container.
It Was An Accident (Bronze): Kill first minion.
Self-Defense (Bronze): Kill 10 minions.
Just Experimenting (Bronze): Used Health Syringe for the first time.
You've Wasted Your Life (Bronze): Idle for five minutes.
Would You Like To Know More? (Bronze): Find your first Asylum File.
Who Is The Jigsaw Killer? (Bronze): Find your first Patient File.
Darwin Would Be Proud (Bronze): Died once.
Give Me Five! (Bronze): First kill with a Mannequin Arm.
Homerun (Bronze): First kill with a Bat.
Sometimes It Sticks (Bronze): First kill with a Nail Bat.
Cleaning Up (Bronze): First kill with a Mop Handle.
Pipe Dream (Bronze): First kill with a Pipe.
Surgeon (Bronze): First kill with a Scalpel.
Penetrated (Bronze): First kill with a Syringe.
You've Been Served (Bronze): First kill with a Table Leg.
You'll Need This Afterwards (Bronze): First kill with a Crutch.
Grave Digger (Bronze): First kill with a Shovel.
Lights Off (Bronze): First kill with a Table Lamp.
Hatchet Job (Bronze): First kill with a Hatchet.
Fire Hazard (Bronze): First kill with fire.
Splitting Headache (Bronze): First kill with Scissors.
Say Hello To My Little Friend (Bronze): First kill with a Gun.
Wait For The Boom (Bronze): First kill with an Explosive Mine.
Whoops! (Bronze): First kill with a Stun Mine.
Choked Up (Bronze): First kill with a Gas Mine.
I'm In Charge (Bronze): Fought first NPC.
Curb Stomp (Bronze): Stomped first Minion to death.
Forced Entry (Bronze): Unlocked first door.
Locksmith (Bronze): Unlock 5 locked doors.
Duress (Silver): Kill 20 minions.
I Can Stop Anytime (Silver): Used 20 Health Syringes.
Kill Or Be Killed (Silver): Killed a Collared Minion with a collar detonation.
Merciless (Silver): Stomped five Minions to death.
Professional (Silver): Unlock 20 locked doors.
Congratulations (Platinum): Acquired all trophies.

Additionally, there are eleven secret trophies:

What Was That?!? (Bronze): First encounter with Pighead.
It's A Trap (Silver): Complete Reverse Bear Trap.
Damaged Goods (Silver): Release Amanda from her trap.
Hit And Run (Silver): Release Jennings from his trap.
Absent Parent (Silver): Release Melissa from her trap.
Aphasia (Silver): Release Oswald from his trap.
Eager Student (Silver): Release Obi from his trap.
Born Victim (Silver): Release Jeff from his trap.
Violence Begets Violence (Silver): Kill the Pighead.
Never Truly Free (Gold): Complete the game using the Freedom Door.
Cost of the Truth (Gold): Complete the game using the Truth Door.